Entertainment TV 16 Stars Who Were on 'Days of Our Lives' Like a sands through the hourglass ... Days of Our Lives is only getting better with time! The long-running soap opera premiered on Nov. 8, 1965 By Janine Henni Janine Henni Twitter Janine Henni is a Royals Staff Writer for PEOPLE Digital, covering modern monarchies and the world's most famous families. Like Queen Elizabeth, she loves horses and a great tiara moment. People Editorial Guidelines Published on November 8, 2021 09:00 AM Share Tweet Pin Email Trending Videos 01 of 15 Mila Kunis Jeff Kravitz/FilmMagic A-lister in training! In one of her first television appearances, Kunis played a young Hope on a 1994 episode. 02 of 15 Lisa Rinna Gary Null/NBC/NBCU Photo Bank Before the cameras panned to her personal life, the Real Housewives of Beverly Hills star played Billie Reed from 1992 to 1995, a role she's returned to reprise on the show several times since. While appearing on PEOPLE in the '90s over the summer, Rinna revealed that her most "surreal" '90s moment was having a fling with her costar Patrick Muldoon — "the guy who played my brother." "Well, not an affair, but a couple of one-night stands with the guy who [played] my brother. Patrick Muldoon and I had like, a thing," she clarified. 03 of 15 Jensen Ackles NBCU Photo Bank/NBCUniversal via Getty Before he shot to stardom with Supernatural, the actor played Eric Brady from 1997 to 2000. 04 of 15 Pamela Anderson Vinnie Zuffante/Michael Ochs Archives/Getty The Baywatch babe stunned as Cindy in 1992. 05 of 15 Pat Sajak CBS via Getty He's known for running the show on Wheel of Fortune, but Sajak had a small role as Kevin Hathaway on Days in 1983. 06 of 15 Kathie Lee Gifford Harry Langdon/Getty A whole decade before she got her start in morning television on Live! With Regis and Kathie Lee, Gifford played Nurse Callihan for one episode in 1975. 07 of 15 Vivica A. Fox Jeff Kravitz/FilmMagic The Independence Day actress had a recurring role as Carmen Silva in 1988. 08 of 15 Jamie Chung Jordin Althaus/WireImage The Dexter star and new mom played Cordy Han on the hit soap in 2007. 09 of 15 Tara Reid Ron Galella/Ron Galella Collection via Getty The American Pie star appeared as Ashley for five episodes in 1995. 10 of 15 LeAnn Rimes Jeff Kravitz/FilmMagic The "Can't Fight the Moonlight" singer graced Days for one episode, portraying Madison in 1995. 11 of 15 Kyle Richards Kyle Richards. David Livingston/Getty Another Beverly Hills Housewife with Days credits to her name, Richards played Casey McGraw in a trio of episodes in 2013. 12 of 15 Ashley Benson Jesse Grant/WireImage Before she starred on Pretty Little Liars, the actress practiced her craft in the role of Abby Deveraux from 2004 to 2007. 13 of 15 John Aniston Frank Carroll/NBCU Photo Bank/NBCUniversal via Getty Talk about the role of a lifetime! Jennifer Aniston's father has played Victor Kiriakis on the soap since 1985, appearing in more than 3,500 episodes, according to his IMDb page. 14 of 15 Andrea Barber Gary Null/NBCU Photo Bank/NBCUniversal via Getty The Full House star got her big break as a child actor in the 1980s, playing Carrie Brady from 1982 to 1986. 15 of 15 Alison Sweeney NBCU Photo Bank/NBCUniversal via Getty Another longtime cast member, Sweeney got her start as Sami Brady from 1993, exiting in 2014 after 21 years. She returned in 2015 in honor of the show's 50th anniversary, and reprised her role once more in 2017.