February 20, 2006 06:00 AM

Though Katherine Heigl takes her role as Dr. Izzie Stevens on Grey’s Anatomy seriously, she lets loose on the set. “T.R. Knight (who plays Dr. George O’Malley) and I mess around a lot,” she says. “We got into a big wrestling water fight after work one day because we get very competitive and aggressive with each other. I think I won that one and he got mad at me and locked me in the bathroom.”

Heigl admits that if she had to have surgery, she wouldn’t want her own Anatomy character to operate on her. “She’s too hesitant – she doesn’t come off with a lot of confidence and she’s a little too emotional,” the actress told us at the show’s first-season DVD party at Hollywood’s Geisha House recently. So, who would she want treating her? “Dr. Burke (Isaiah Washington) – he seems to know what he’s doing.”

Ready for Their Close-up

Real-life couple Jessica Biel and Chris Evans had no problem generating onscreen heat while filming sexy scenes for their indie flick London. “When you have a sense of security, you know they’re going to respect your boundaries,” says Biel. Evans, who also played Johnny Storm in Fantastic Four, agrees. “The scenes demanded a lot of comfort and intimacy. If you have that already off camera, it definitely translates the second they’re rolling.”

The tough part for Biel was doing the movie’s nude scenes. “I just didn’t feel comfortable exposing myself and putting it out there,” she told us about opting for a body double at the drama’s recent Hollywood premiere. “I don’t know if I ever will.”

Caught in the Act

Britney Spears (right), shopping with her assistant Felicia Culotta at the accessories counter of L.A. store Fred Segal.

Bruce Willis, drinking only bottled water during a visit to New York City club Home. Meanwhile, at the next table over, Mena Suvari was doing shots with pals.

George Clooney, shooting a scene for his film The Good German at the Santa Monica Promenade.

• BRENDA RODRIGUEZ, NICHOLAS WHITE, MARISA LAUDADIO, MARK DAGOSTINO and VANESSA DIAZ

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