Steve Granitz/WireImage
April 09, 2015 11:45 AM

While Dr. Mehmet Oz believes Giuliana Rancic when she says she does not have an eating disorder, that doesn’t mean he doesn’t have concerns about her health.

“I’m worried about her,” Oz told PEOPLE at Wednesday’s New York City reception for The Hollywood Reporter‘s 35 Most Powerful People in Media.

“I’m not worried that she has an eating disorder, but I am worried about her,” said the host of The Dr. Oz Show just hours after his own on-camera interview with Rancic aired.

Speaking with Oz, Rancic denied claims that she has an eating disorder and blamed her small size on medication she has taken since being diagnosed with breast cancer in 2011. (Rancic also has spoken with PEOPLE about the scoliosis that makes her shoulder blades protrude.)

Rancic, 40, did express a desire to gain weight, and Oz agrees with her – but not just to put an end to the rumors.

“She knows she needs to gain weight, that’s the sign that she doesn’t have an eating disorder,” he told PEOPLE.

“The problem is that, if she has to battle something like cancer again that she won’t be able to handle it,” noted Oz, 54, who said on the episode that she sometimes looks “dangerously thin.”

Rancic also revealed to PEOPLE recently that she knows she’s too thin, saying that originally she thought the cancer was back.

Warned Oz, though: “What kills us isn’t heart disease or cancer, it’s when our bodies aren’t strong enough to handle the treatment. She would be too frail.”

Dr. Oz is confident the E! News host can gain weight: “She’s been bigger. She’s never been very big, but she hasn’t always been this thin.”

What are the doctor’s orders? “I told her to get more exercise,” said Oz.

RELATED: Giuliana Rancic: ‘I Know I’m Too Thin’

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