Trump, 70, called out Ryan and other Republicans for giving him “zero support” despite “winning the second debate in a landslide” before proclaiming that Democrats are a more united party.
He turned his attention to Ryan directly, calling the House Speaker a “very weak and ineffective leader.”
The GOP candidate then declared he was free to run his campaign according to his own will.
“It is so nice that the shackles have been taken off me and I can now fight for America the way I want to,” he tweeted.
He later took aim at others within his own party, maintaining that Republicans who defy him are more “difficult” than his Democratic opponent.
“Disloyal R’s are far more difficult than Crooked Hillary. They come at you from all sides. They don’t know how to win – I will teach them!”
Later, coming out a weekend tailspin over his graphically crude language about women, Trump also unloaded (again) on Vietnam-era war hero and 2008 Republican presidential nominee, Sen. John McCain, tweeting on Tuesday morning that McCain is “very foul mouthed.”
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Twitter users were quick to respond to Trump’s latest tirade.
Ryan declared he would no longer defend Trump or campaign with him for the rest of the election season in a Monday conference call with House Republicans. He continued that party lawmakers wouldn’t face backlash for openly opposing the business mogul. However, AshLee Strong, a spokeswoman for the House Speaker, told ABC News that there was no change in Ryan’s endorsement of Trump.
Ryan’s comments come after Friday’s release of a 2005 video featuring Trump making offensive comments about groping women, and one day after a no-holds-barred presidential debate between Trump and Democratic nominee Hillary Clinton.
Ryan, 46, also said that House Republicans must focus on building a strong Republican Congress in the event that Clinton is elected to the Oval Office, said Politico.
Trump previously responded to Ryan’s comments on Twitter Monday afternoon.
Trump’s senior communications adviser, Jason Miller, also addressed the comments.
Ryan wasn’t the only Republican to publicly denounce Trump’s comments about women: politicians Jeb Bush, John Kasich, Jeff Flake and Mitt Romney all spoke out against the GOP nominee in light of the 2005 recording.