Actress Karen Gillan also defended Chris Pratt on social media
Zoe Saldana, Russo Brothers, Chris Pratt
Zoe Saldana, Chris Pratt, Russo Brothers
| Credit: Michael Stewart/WireImage; Oleg Nikishin/Epsilon/Getty; Albert L. Ortega/Getty

Chris Pratt is receiving more support from his famous friends after an Internet challenge dubbed him the "worst Hollywood Chris."

On Tuesday, Zoë Saldana defended her Guardians of the Galaxy and Avengers: Endgame costar after filmmaker Amy Berg asked people on Twitter over the weekend which Hollywood Chris "has to go"? — which resulted in Pratt, 41.

"No matter how hard it gets, stick your chest out, keep your head up and handle it," Saldana, 41, wrote on Twitter, quoting the late Tupac Shakur. "You got this @prattprattpratt," the actress added. "Your family, friends, colleagues & everyone who's ever crossed paths with you knows your heart and your worth!"

Karen Gillan, who has also starred in the Marvel films, came to Pratt's defense as well, retweeting Saldana's post and writing, "That's right!!!" with three heart emojis.

Anthony and Joseph Russo, who directed four of the Marvel Cinematic Universe films, supported Pratt with a heartfelt note about the actor on their Instagram Story.

"Chris Pratt is a good man who cares deeply about his family, friends, and co-workers," the directors wrote. "He has always shown incredible love and generosity to our crews, to his fans, to charities, and everyone he encounters. Normally, it is our policy not to engaged in, or lend credence to, the toxic cycle of misinformation and false accusations that have become so prevalent on social media."

"However," they added, "we are disheartened by the animosity being directed at him. Perhaps if we were able to redirect this energy toward self-improvement, we might find a path to a better world..."

chris pratt, russo brothers
Credit: Russo Brothers/Instagram

Pratt's wife, Katherine Schwarzenegger Pratt, was one of the first people to publicly defend the actor by responding to an Instagram post by E! News that asked followers the same question as Berg.

"Is this really what we need?" the new mom wrote on Tuesday. ""There's so much going on in the world and people are struggling in so many ways. Being mean is so yesterday. There's enough room to love all these guys. Love is what we all need not meanness and bullying. Let's try that."

Katherine Schwarzenegger Chris Pratt
Credit: Instagram

Pratt's Avengers: Endgame costars, Robert Downey Jr. and Mark Ruffalo, also replied to the Twitter challenge, writing on their respective social media accounts.

"What a world... The "sinless" are casting stones at my brother, Chris Pratt...," Downey Jr., 55, wrote on Instagram alongside a photo of himself and Pratt on the set of the 2019 blockbuster film. "A real Christian who lives by principle, has never demonstrated anything but positivity and gratitude... AND he just married into a family that makes space or civil discourse and (just plain fact) INSISTS on service as the highest value."

"If you take issue with Chris,,, I've got a novel idea," Downey Jr. continued. "Delete your social media accounts, sit with your OWN defects of character, work on THEM, then celebrate your humanness... @prattprattpratt I #gotyerbackbackback."

Katherine Schwarzenegger, Robert Downey Jr and Mark Ruffalo, Chris Pratt
Credit: Getty Images (3)

Ruffalo, 51, tweeted, "You all, @prattprattpratt is as solid a man there is."

"I know him personally, and instead of casting aspersions, look at how he lives his life," he continued. "He is just not overtly political as a rule. This is a distraction. Let's keep our eyes on the prize, friends. We are so close now."