Bradley Cooper and Jennifer Esposito wed in December 2006 but officially called it quits by May 2007, after four months of marriage

Jennifer Esposito has weighed in on her ex-husband Bradley Cooper‘s powerful connection with Lady Gaga.

During Gaga and Cooper’s intimate Oscars performance on Sunday evening, David Spade snapped a photo of the highly-speculated A Star Is Born costars.

While on stage, the on-screen lovers shared a piano bench, singing a stripped-down take on the track cheek-to-cheek before affectionately gazing into each other’s eyes, with Cooper wrapping his arm around Gaga’s waist.

“Is there any chance these 2 aren’t f—?” he jokingly asked in the Instagram caption, prompting many users to share their thoughts.

David Spade’s Instagram
| Credit: David Spade Instagram

One of those users included Esposito, 45, who provided one simple reaction to Gaga’s relationship with her ex-husband, first captured by Comments by Celebs.

“Ha,” the actress simply wrote.

Jennifer Esposito’s comment
| Credit: Jennifer Esposito Instagram

Cooper, 44, and Esposito wed in December 2006 but officially called it quits by May 2007, after four months of marriage. Since 2015, the actor has been dating model Irina Shayk.

Gaga, meanwhile, was engaged to Christian Carino for approximately four months before the pair officially ended things, her rep confirmed to PEOPLE exclusively last Tuesday.

In Style and Warner Bros. 2007 Golden Globe After Party - Inside
Bradley Cooper and Jennifer Esposito
| Credit: John Sciulli/WireImage
25th Annual Screen Actors Guild Awards - Inside
Christian Carino and Lady Gaga
| Credit: Kevin Mazur/Getty Images for Turner

Fans have long been enamored by Gaga and Cooper’s on- and off-screen chemistry, to the point where some online wanted their passionate performance on Sunday to end with a kiss.

Instead, Gaga and Cooper smiled and hugged as they walked off the stage. Their embrace continued backstage as the two were met with a swarm of claps from well-wishing production staff.

“Did I nail it?” asked Gaga. Taking in the congratulations, she looked at Cooper and said, “I’m so f—ing proud of you!”

Lady Gaga Bradley CooperCredit: ABC
Lady Gaga and Bradley Cooper

With only a few seconds to get back to their seats, a handler disengaged Gaga from the mic-pack attached to the back of her dress — and Cooper and Gaga, side by side, made their way to their seats via the stage.

During the commercial break following their duet, the pair came out arm-in-arm to huge cheers and another standing ovation from the entire house. Cooper kissed and hugged Shayk, 33, when he got back to his seat, and the model congratulated Gaga, whom Shayk cheered on throughout the night.

After “Shallow” won the award for Best Original Song, Gaga also sent love to Cooper in a teary acceptance speech.

“Bradley, there is not a single person on the planet that could’ve sung this song with me but you,” she said. “Thank you for believing in us, thank you so much.”

Lady Gaga and Bradley Cooper
| Credit: Kevin Winter/Getty

Spade and Esposito weren’t the only ones to publicly speculate about the costars’ electrifying chemistry. Mel B also recently provided her input after watching their steamy performance.

On Monday, the Spice Girls singer, 43, criticized Gaga and Cooper during Good Morning Britain‘s Academy Awards telecast, explaining that she couldn’t help but think about Cooper’s girlfriend the whole time.

"America's Got Talent" Season 13 - Red Carpet Kickoff
Mel B
| Credit: JB Lacroix/WireImage

I felt so uncomfortable for Bradley’s girlfriend, oh my gosh,” Mel B recalled of the moment, according to video captured by The Sun.

Agreeing that the duo had “the look of love,” Mel B hoped that the energy between Cooper and Gaga was just for show.

“I would like to think it was part of the whole performance, because there’s a women’s code and hopefully that’s not,” she said. “Hopefully it’s only professional.”