They Said What!: The Wackiest Quotes from the 2010 VMAs
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"Wake up Handler! You're a mess. Do you think anyone wants to work with a drunk? Take it from me. They don't."
– Recently rehabbed Lindsay Lohan, handing host Chelsea Handler some advice during the show's opening skit
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"So so far I'm the oldest chick with the biggest hair and the littlest costume."
– Cher, 64, after taking the stage in her iconic "If I Could Turn Back Time" bodysuit 21 years after she debuted it
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"I never thought I'd be asking Cher to hold my meat purse."
– Lady Gaga, during her acceptance speech for winning video of the year for "Bad Romance"
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"Maybe we'll bite someone. You bark. I'll bite."
– True Blood vamp Evan Rachel Wood to costar and co-presenter Joe Manganiello, on what VMAs surprise may lay in store for them
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"I'm a huge fan of seamen, thank you."
– Jackass star Johnny Knoxville, after being complimented on his nautical attire on the MTV white carpet
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"Have fun tonight. He's stiff."
– Katy Perry, on handing Eminem's Moonman for best male video to single star Nicki Minaj
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"It's okay, life is a tough crowd. 32 is still growing up now."
– Taylor Swift, taking aim at Kanye West while performing an untitled track from her new album
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"Let's have a toast for the douchebags."
– Kanye West, getting in the last word while performing his unreleased track, "Runaway," during the show's closing performance