Roseanne Barr’s ABC Family series “Domestic Goddess” is being interrupted as its star must undergo surgery next Wednesday, says the Hollywood Reporter.

Earlier this week, according to Barr’s assistant, Becky Pentland, physicians informed Barr, 50, that she needs a hysterectomy. No further medical details were reported.

Although production on the 13 episodes of “Goddess” is already underway, staff members were reportedly informed that the show would be on hiatus until further notice.

A network spokeswoman said it remains unclear if the show would be ready in time to meet the scheduled Sept. 20 premiere date.

The development of “Goddess” also has been the subject of an ABC reality TV series, “The Real Roseanne Show,” which has already completed production and is up and running.

Meanwhile, Barr’s former TV husband, John Goodman, 51, is going to take another stab at his own sitcom, having sealed a deal with CBS for a new show to launch fall 2004, says the Hollywood Reporter.

Should the greenlight stay on, the series would mark the hefty star’s first starring TV role since FOX’s short-lived comedy “Normal, Ohio,” in the 2000-01 season. He also had a small role in the drama series “Now and Again,” which ran on CBS in the 1999-2000 season.