Look Who's 'Fiftysomething!'

Twenty years after thirtysomething, the show's stars dish about growing older and looking great

BACK TOGETHER

GEORGE HOLZ

It's been 20 years since the 1987 debut of thirtysomething, but the ABC hit's four female stars – Polly Draper, 51, Mel Harris, 50, Melanie Mayron, 54, and Patricia Wettig, 55 – are as close as ever. Reunited as ambassadors for Tylenol's Keep Moving arthritis-prevention campaign, the women sat down with PEOPLE's Pamela Warrick to talk about how they're looking great as fiftysomethings.

(More information on the Keep Moving program, a joint venture launched by Tylenol and the Arthritis Foundation to educate Baby Boomers about ways to ease the aches and pains of aging, is available at justkeepmoving.com.)

MEL HARRIS

Ron Galella/WireImage; GEORGE HOLZ

Played: Happily married Hope Murdoch Steadman
Now: The mom of two (Byron, 23, and Madeline, 17) remains a TV regular, appearing on shows like Criminal Minds, and says, "I believe in love," despite being in the midst of a fifth divorce.
Facing facts: "I can certainly, honestly say, I do visit my dermatologist. Regularly!"

PATRICIA WETTIG

Ron Galella/WireImage; GEORGE HOLZ

Played: Stay-at-home mom Nancy Krieger Weston
Now: Wettig, who's been married to thirtysomething costar Ken Olin for 25 years, stars on Brothers amp Sisters, which Olin executive produces; their son Cliff, 24, is one of the show's writers while daughter Roxy, 21, has a small recurring role as Michelle.
Gray matter: "If I was a farmer, I'd have a long gray ponytail. But I wouldn't show up today with gray roots. If everybody is having surgery and you haven't, you look old."

POLLY DRAPER

Courtesy Everett Collection; GEORGE HOLZ

Played: Confused career woman Ellyn Warren
Now: Draper has been married to musician Michael Wolff since 1992, and has two sons, Nat, 12, and Alex, 9, whom she directs in Nickelodeon's The Naked Brothers Band.
Jump start: I run three miles a day, wherever I am. I also do weights and I jump rope. Twenty years ago, I started jump roping because you can take a jump rope anywhere."

MELANIE MAYRON

Courtesy Everett Collection; GEORGE HOLZ

Played: Free-spirited photographer Melissa Steadman
Now: Mayron is a single mom to twins Miles and Olivia, 8, and is getting set to launch a diaper cream later this year.
Personal uplift: "I've still got my pregnancy weight from years ago, the final 20 lbs. I haven't lost! I had my breasts reduced and lifted last year. After the babies, they just ... needed it."

For more from the women of thirtysomething, including the secrets to a happy marriage and how it feels to grow older in Hollywood, check out the new issue of PEOPLE, on newsstands now