The Grey’s Anatomy star filed for divorce on April 11, according to documents obtained by PEOPLE.
Williams, 35, wed his longtime girlfriend Drake-Lee, a real estate broker, in Los Angeles in September 2012. At the time, they had been dating for over five years. They first met while Williams was working as a schoolteacher in New York.
“She’s been with me through all different facets of my career,” Williams told USA Today in 2010. “She’s stuck with me through thick and thick and thick and thin. We know each other in and out.”
Williams also told PEOPLE in 2009 that he was in awe of her confidence and independence: “She is her own person, he said. “Being intelligent and self-made is a big deal for me.”
TheJasmineBrand.com first reported the news of the split, and Williams’ rep did not immediately respond to PEOPLE’s request for comment.