PEOPLE confirmed Reynolds, 84, was rushed to the hospital from her home in Beverly Hills Wednesday afternoon for treatment of a possible stroke. She died several hours later.
Hollywood mourned the Oscar-nominated star of The Unsinkable Molly Brown and Singin’ in the Rain on social media.
Debra Messing, Reynolds’ TV daughter on Will & Grace, expressed feeling “heartsick” over the news. “So heartsick,” she wrote. “Debbie went to be with Carrie. It’s such a devastating 1,2 punch. She was my ‘mom’ for years and I loved her dearly. A legend.”
Messing’s Will & Grace costar Sean Hayes shared a photo of himself laughing with the late Reynolds. “It is beyond astonishing that both @carriefisher & @DebbieReynolds1 have both left this earth,” he wrote on Twitter. “I overwhelmingly adored & admired them both.”
And another Will & Grace alum, Eric McCormack, expressed his sadness over the loss of both Reynolds and Fisher. “The combination of the loss of @carriefisher & then her mom @DebbieReynolds1 is too much,” he Tweeted. “I’m really at a loss here… #toomuch16”
Other famous friends and fans quickly expressed their grief. Madonna, Josh Brolin, Martha Plimpton and Marion Cotillard all choose a touching black and white photo of a young Fisher watching her mother perform on stage.
“Sweetest Picture ever of Carrie Fisher watching her mother Debbie Reynolds on stage!” Madonna captioned the photo. “Hug Your mother today! Then Hug your daughter!”
Actor Albert Brooks, who played Reynolds’ son in the 1996 comedy Mother, paid tribute to his “legend” of a movie mom.
“Debbie Reynolds, a legend and my movie mom,” Brooks wrote on Twitter. “I can’t believe this happened one day after Carrie. My heart goes out to Billie.”
Dame Joan Collins shared a sweet photo of herself hugging Reynolds and a heartfelt message on Twitter: “Truly heartbroken to hear @DebbieReynolds1 has died,” she wrote. “She was a wonderfully warm friend and colleague. Praying for Todd & Billie.”
Fisher’s half-sister Joely Fisher tweeted that she is “inconsolable” after learning of Reynolds’ passing.
“Some of the magic people have left the tribe…for the moment I am inconsolable,” she wrote.
“Debbie Reynolds was pure class,” talk show host Larry King wrote on Twitter. “She was loving, talented, beautiful, unsinkable. I feel sorry for anyone who never got a chance to meet her.”
Ellen DeGeneres expressed her thoughts and love for Reynolds and Fisher’s family. “I can’t imagine what Carrie Fisher and Debbie Reynolds’ family are going through this week,” she tweeted. “I send all my love.
“So blown away and saddened by this Debbie Reynolds news a day after her daughter, Carrie passes away,” he wrote. “So much luv & strength to their family.”
Mark Hamill, who starred opposite Fisher in the original Star Wars trilogy as well as Star Wars: The Force Awakens, took to Twitter, writing “#CruelCruelYear.”
Former Disney star Kimberly J. Brown, who costarred with Reynolds’ in the TV movie Halloweentown, posted a lengthy tribute on Facebook along with a photo of herself with Reynolds on the set of the 1998 Disney Channel movie.
“What do you say about a woman who had such an impact on your life both professionally and personally? Debbie lived her life like all of us should, to the fullest. She was bold, funny, and had the biggest heart,” she wrote. “‘Being normal is vastly overrated’ is a quote from ‘Halloweentown,’ and how fitting it is that her character spoke it. Her generosity, talent, and loving spirit made her anything but normal. Thanks for the magic, Debbie. Rest in peace.”
Family Guy creator and Reynolds fan Seth MacFarlane offered up a tribute to the late actress with a link to his favorite Reynolds recording. “She was one of the last of the true H’wood talents,” he tweeted. “Actress, singer, dancer.”
Musician Sean Lennon, son of John Lennon and Yoko Ono, posted a photo and a long tribute message on Facebook.
“I’m absolutely speechless with the news of Debbie passing just a day after her daughter,” he wrote. “I knew how close they were and because of Carrie I have so many wonderful memories of Debbie in her house next to Carrie’s. They were so absolutely close it seems clear that Debbie wanted to be with her daughter. Carrie and Debbie’s relationship was a template for mine with my mother. I’m so stunned.” Lennon went on to add his support for Reynolds’ granddaughter and Fisher’s daughter, Billie Lourd. “I can’t imagine how Billie feels, please concentrate your energies on helping her through this tornado of tragedies. I can’t imagine losing two such pillars in so short a time. I love you Billie. And I love you Carrie and Debbie always.”
Designer Zac Posen shared a clip of a Reynolds musical number from the hit film Singin’ in the Rain.
“#Debbiereynolds age 19 in my favorite musical #singingintherain,” he wrote. “Debbie was perfection throughout her 60 year career.!! A real #Star and icon.”
Tracee Ellis Ross paid tribute to both Fisher and Reynolds with a collage of the mother-daughter duo.
“A daughter and now her mother. Two women who shared their love and talents and lives with the world,” she said. “#DebbieReynolds was a Hollywood Royalty and a legendary lady. sending so much love to the family and friends.”
Selma Blair honored Reynolds and Fisher with a throwback photo of the two.
“I like to think of them like this right now,” she captioned the photo of the mother and daughter smiling and holding hands. “I met Debbie Reynolds on the set of in & out. I was in awe. Her charm and beauty and wit. And then, afterwards, with Carrie, where we would go down the hill and pull pranks on ms Reynolds come night time. They were an amazing pair. Two inspiring women that will be missed by everybody. My heart goes out to the family. Only love. And misses. It will be a while til I smile behind my face as Carrie would say. peace to you both.”
Interview with a Vampire author Anne Rice also took to Facebook to pay tribute to the late actress. “Everyone is in shock here. Debbie Reynolds has died,” she wrote. “We have lost her too. We are all sad. I grew up in the 50’s when Debbie Reynolds was the rage. She and Eddie Fisher were the dream couple. And Debbie was in so many fun movies. And in later years I discovered her remarkable talent in Gene Kelley’s ‘Singing in the Rain.’ How terribly sad that she lost her daughter, Carrie, and now we have lost her. Carrie and Debbie both gone.”