The talk-show host, who is friends with Jennifer Aniston, says she's "not a fan" of The Tourist star
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Chelsea Handler is once again making it clear she’s on Team Aniston.

The comedian takes yet more jabs at Angelina Jolie while praising her pal Jennifer Aniston in a new interview with Glamour magazine.

When asked about Jolie, the Chelsea Lately host tells Katie Couric, who conducted the interview, “I’m not a fan. She just doesn’t come off to me as a sincere woman. She seems like a woman that you’d really want to avoid.”

Aniston, on the other hand, is described by Handler as “very” funny when asked which women amuse her. “Jennifer Aniston makes me laugh,” she said. “She’s irreverent and hilarious, and she sends me really, really funny e-mails.”

When asked about her biting brand of comedy, Handler says she’ll go for anyone she deems worthy of the Handler treatment.

“I think it’s important to be politically incorrect,” she says. “You don’t want to be nasty, and you don’t want to be malicious. But it’s okay – I mean, funny trumps everything in my mind.”

However her nasty remarks about Jolie – and racially insensitive jokes about some of Jolie’s children – during a comedy show in Newark, N.J., have caused a stir.

In her defense, Handler says she’s been picking on Jolie for years, before she was buddies with Aniston, who was married to Jolie’s partner Brad Pitt.