January 30, 2016 08:30 PM

Hollywood’s top actors and actresses opened the 2016 Screen Actors Guild Awards with a bang – and a laugh!

The stars opened the show with the annual “I’m an Actor” segment – one of the most popular traditions of the ceremony, known for allowing some of Hollywood’s biggest names to share personal stories about their craft.

Queen Latifah got big applause for talking about typecasting and the struggles she’s endured to get roles.

“I’ve often been told I’m not thin enough. I’m not white enough,” she said. “I’m not short enough. I’m not man enough. Damn it – I am enough. I am Queen Latifah, and I’m an actor!”

Check out PEOPLE’s full 2016 SAG Awards coverage and complete winners list!

The Big Bang Theory‘s Kunal Nayyar recalled playing a terrorist in CSI for his first role.

“My first professional acting job was playing a terrorist on a very popular TV show. I couldn’t grow a mustache so they had to glue one on me. It was crooked,” SAID Nayyar. “Then Mark Harmon punched me in the face. It was the greatest moment of my life. My name is Kunal Nayyar, and I am so proud to be an actor.”

Transparent‘s Jeffrey Tambor noted that if 69 years ago you’d told him he’d be nominated for playing a character named Maura Pfefferman, “I would have said well I wouldn’t have said anything, because I was only one.”

Veep‘s Anna Chlumsky said her favorite note from a casting agent was “Now just take the energy down 90 percent,” while Mr. Robot‘s Rami Malek said he used to think he was insane, because as a child he would lock himself in a room and make up characters – but he learned as an adult he was “not insane,” he was in fact “an actor.”

The 22nd annual Screen Actors Guild Awards were presented live on TNT and TBS.

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