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A CUT ABOVE
Liz Haines's shout-out is more than a sentiment – it's a work of art.
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ALL DRESSED UP
Perhaps the furthest – and most far-out – birthday wish comes from Mad gal Veronika, who sends greetings all the way from Russia.
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Meghamn Mariane's extensive DVD collection cost her a pretty penny, so it's definitely worth a spot in our gallery.
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Is it just us, or does it seem that well-wisher Marco Antonio Todisco has a specific set of favorite Depp characters?
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SEALED WITH A KISS
If the star is still currently single, he can at least count on a birthday smooch from puckered-up partisan Christin.
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ROOM WITH A VIEW
We appreciate self-proclaimed "biggest fan" Taramarie Mitravich's Depp dedication – and hope he appreciates her birthday wishes, too!
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WORDS FOR FRIENDS
Well said, Brittany Joliv. And Johnny, please don't Cry, Baby – 50 is the new 40!
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We give Deb Carlton a 10 for creativity, a 10 for execution ... and an 11 for slight creepiness (we kid, we kid!).
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IT'S YOUR TURN!
Are you Johnny Depp's biggest fan? Do you want to wish him a happy 50th, too? Upload your photos here or share them with us on Instagram or Twitter using #YTdeppbday, and they could appear on People.com!