The off-again, on-again, off-again five-year marriage of Nicolas Cage, 36, and “Little Nicky” actress Patricia Arquette, 32, is . . . off again. She filed for divorce on Friday in Los Angeles Superior Court, citing “irreconcilable differences.” Earlier this year, he had filed for divorce, for the very same reason. But then, five weeks later, in early April, they reconciled and he reportedly withdrew his divorce petition. From the start, it has been an odd coupling. Nine months after they were wed in 1995, the two separated, it was reported, though they continued to appear in public together as a twosome. In 1996 (the same year he won an Oscar for “Leaving Las Vegas”), lawyers drew up legal separation papers for the Cages. In this latest filing, the two, who separated on Nov. 1, have already divided their assets and debts, according to court documents. Publicists for both performers call the dissolution of the marriage amicable.