1 of 10
Why do we love the season's hottest new show? Let's look at how each character operates: Dr. Derek "McDreamy" Shepherd (Patrick Dempsey, far right) has his hair; Dr. Meredith Grey (Ellen Pompeo, to his left), her heart; Dr. Christina Yang (Sandra Oh), her mouth; Dr. Alex Karev (Justin Chambers), testosterone; Dr. Izzie Stevens (Katherine Heigl), estrogen; and finally, Dr. George O'Mally (T.R. Knight) – the eyes.
2 of 10
The TV cook has the recipe for a really sweet year:
Mix four shows on the Food Network with five best-selling cookbooks.
Turn up the heat with the November launch of Every Day with Rachael Ray magazine and a talk show slated for next fall.
Blend in a September wedding to lawyer John Cusimano.
Maintain homespun sassiness. "I live exactly the same way now as I did," says Ray. "I just have better shoes."
3 of 10
The overnight sensation, who had five films in '05, says he "became an actor this year, part of the craft." The Academy may agree: He already has Oscar buzz for his performances in Crash and Hustle & Flow.
4 of 10
The comedian, who starred in her own concert movie, Jesus Is Magic, jokes of her new level of fame: "I can't go anywhere without being chased by teenage girls – they think I'm Raven-Symoné."
5 of 10
FALL OUT BOY
Perception: Since "Sugar, We're Going Down" sent the Chicago foursome up the charts, they're living the high life.
Reality: "We're four totally awkward, nerdy guys," says singer Patrick Stump, "with the coolest job in the universe."
6 of 10
Signs you could be Hollywood's new It girl:
1. You do it all: Horror (Red Eye), comedy (Wedding Crashers), romance (The Notebook).
2. You're said to be dating a costar (The Notebook's Ryan Gosling).
3. You're likened to a screen queen: "She hates being compared," says Wedding Crashers director David Dobkin, "but I often said to her, 'You can be Julia Roberts.' "
7 of 10
As Comedy Central's version of Ted Koppel, he got his own Daily Show spinoff, The Colbert Report. How does he keep it fake? "Go with your gut. Facts can be misleading."
8 of 10
The 16-year-old golfer's accomplishments in 2005:
Earned approximately $10 million with Sony and Nike.
Came thisclose to making the cut on the PGA men's tour.
Scrubbed toilet. "I'm still responsible for cleaning my bathroom," she says.
9 of 10
Up for eight Grammys, the RampB singer sums up his year this way: "I've toured the world, made a lot of people happy." Good enough for us.
10 of 10
The frisky cast of the MTV reality show captivated a nation with their round-robin romances and still found time to do some serious networking: LC's getting her own spinoff show, The Hills, Talan (a.k.a. Kimberly Stewart's split-second fiancé) is cutting an album and Kristin signed on to appear in the thriller 88 Minutes with Al Pacino. This is what it means to be young, rich and constantly trailed by a camera.
Everything We Know About Jennifer Lopez and Alex Rodriguez's Romance — So Far
Ellen Pompeo, Amy Schumer and More Female Celebs Who've Spoken Out About the Hollywood Wage Gap
Behind the Scenes of Children of a Lesser God's First Producer Meeting with Nyle DiMarco