The 29-year-old musician – who is the highest-paid woman on YouTube with over 7.8 million subscribers and 1 billion channel views – will join Dion as she covers Queen’s “The Show Must Go On.”
The performance comes as Dion, 48, receives the BBMA’s ICON lifetime achievement award. Dion released a single of the cover, as a preview.
“René loved the fans so much,” Dion exclusively told PEOPLE. “He loved the business so much. He had such respect for the artist, for the stage – for everybody who worked to make a show work. The show must go on for him. No matter what [happens in life] we have to make it work, we have to make it happen. It represents him very well.”
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The song could be an anthem for Stirling as well, who has opened up in the past about her struggles with anorexia and depression.
“Once I realized that there was a problem, that’s when I could change. I knew that I could be happy again. And it was a long road, and it took a lot of looking inward and retraining my brain to think positively.”
Stirling’s sophomore album Shatter Me earned her a 2015 BBMA honor for Top Dance/Electronic Album, after debuting number two on the publication’s Top 200 album chart. Her third album is scheduled to be released this summer.
• Reporting by JANINE RUBENSTEIN