Heath Ledger, 25, & Naomi Watts, 36
A 10-year age difference reportedly did in the two-year relationship.
Nicky Hilton, 21, & Todd Meister, 34
Two months after their Vegas wedding-on-a-whim, the pair began work on an annulment.
Tom Cruise, 42, & Penélope Cruz, 30
Hectic schedules were blamed for the end of their three-year romance.
Katie Couric, 47, & Tom Werner, 54
The bicoastal commute (she’s in N.Y.C., he’s in L.A.) took its toll after four years. Couric has since dated jazz trumpeter Chris Botti, 42.
Barbie, 45, & Ken, 43
After four decades, Barbie asked Ken to vacate the Dream House.
John Stamos, 41, Rebecca Romijn, 32
Married 5½ years, the two parted ways amicably.