Who’s handsome? What’s gorgeous? Where does sublime reside? Among our fabulous 50 this year, charisma counts as much as comeliness. Joining such classics as a bonny Mel Gibson, a To Die For Nicole Kidman, a stripped-down Demi Moore and radiant runway goddess Tyra Banks (pictured here and on page 104) are Sandra Bullock, Whose kicky charm has men Speeding; X-Filer David Duchovny, who sends fans to the twilight zone with his geek-chic visage; and Nanny star Fran Drescher, who shares her program for pumping up her assets. So, traveling over the following 78 pages, feel free to sightsee on the main thoroughfares and explore the back roads too. Wherever you end up, you’ll be energized—and, perhaps, a little flushed—by the journey.